Huntington's disease is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and dementia.Cognition was also characterized at different stages of Huntington's disease (HD) and in the prodrome prior to the diagnosis engine is given.
Although the clinical diagnosis of HD is based on the manifestation of motor disorders, impairments associated with the first plan has been growing for several reasons.
First, understand the research on the most debilitating aspects of HD suggested that cognitive and behavioral changes in the burden for families and are more closely related functional decline is predictive of institutionalization.
Second, cognitive impairment are obviously at least 15 years before the time is given to the diagnostic engine.
Finally, cognitive abilities with biological markers such as brain atrophy is associated with the blood of the first brain-derived neurotrophic factor and insulin-like growth factor
Efforts are being made to develop valid and reliable measures of cognition in the prodrome and at all stages of HD, so that clinical trials with cognitive scores.
